Intracerebroventricular opioids for intractable pain
نویسندگان
چکیده
منابع مشابه
Intracerebroventricular Pain Treatment with Analgesic Mixtures including Ziconotide for Intractable Pain.
Intracerebroventricular (ICV) administration of opioids for control of intractable cancer pain has been used since 1982. We present here our experience of intracerebroventricular administration of pain treatments including ziconotide associated with morphine and ropivacaine for patients resistant to a conventional approach, with nociceptive, neuropathic, or mixed pain. These clinical cases were...
متن کاملOpioids for neuropathic pain.
BACKGROUND The use of opioids for neuropathic pain remains controversial. Studies have been small, have yielded equivocal results, and have not established the long-term risk-benefit ratio of this treatment. OBJECTIVES To assess the efficacy and safety of opioid agonists for the treatment of neuropathic pain. SEARCH STRATEGY We searched the Cochrane Central Register of Controlled Trials (2n...
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BACKGROUND Since the 1970s, when endogenous opioids and opioid receptors were first isolated in the central nervous system, attempts have been made to optimize opioid therapy by delivering the medication centrally rather than systemically. Although the vast majority of cancer patients obtain satisfactory pain relief from individualized systemic treatment, there remain the few whose pain is refr...
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The number of available opioid preparations, each with differing chemical properties, structure and opioid receptor affinity, increases with time. The efficacy of these opioids in the treatment of pain arising from a diverse range of disorders is beyond question. With the passage of time, the list of those conditions where an opioid is recommended as a treatment option increases, and that list ...
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Patients with moderate to severe malignancy-related pain frequently require the use of opioid pharmacotherapy. Unfortunately, many cancer patients continue to be prescribed subtherapeutic doses of pain medications resulting in undo suffering and diminished quality of life. The choice of analgesic pharmacotherapy should be individualized and based on the intensity and etiology of pain reported b...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2012
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2012.04201.x